منابع مشابه
Calbindin D28k-Immunoreactivity in Human Enteric Neurons
Calbindin (CALB) is well established as immunohistochemical marker for intrinsic primary afferent neurons in the guinea pig gut. Its expression by numerous human enteric neurons has been demonstrated but little is known about particular types of neurons immunoreactive for CALB. Here we investigated small and large intestinal wholemount sets of 26 tumor patients in order to evaluate (1) the prop...
متن کاملCritical role of calbindin-D28k in calcium homeostasis revealed by mice lacking both vitamin D receptor and calbindin-D28k.
Calbindin (CaBP)-D28k and CaBP-D9k are cytosolic vitamin D-dependent calcium-binding proteins long thought to play an important role in transepithelial calcium transport. However, recent genetic studies suggest that CaBP-D28k is not essential for calcium metabolism. Genetic ablation of this gene in mice leads to no calcemic abnormalities. Genetic inactivation of the vitamin D receptor (VDR) gen...
متن کاملInhibition of West Nile Virus by Calbindin-D28k
Evidence indicates that West Nile virus (WNV) employs Ca(2+) influx for its replication. Moreover, calcium buffer proteins, such as calbindin D28k (CB-D28k), may play an important role mitigating cellular destruction due to disease processes, and more specifically, in some neurological diseases. We addressed the hypothesis that CB-D28k inhibits WNV replication in cell culture and infected roden...
متن کاملThe role of parvalbumin and calbindin D28k in experimental scrapie.
AIMS Prion diseases are generally characterized by pronounced neuronal loss. In particular, a subpopulation of inhibitory neurones, characterized by the expression of the calcium-binding protein parvalbumin (PV), is selectively destroyed early in the course of human and experimental prion diseases. By contrast, nerve cells expressing calbindin D28 k (CB), another calcium-binding protein, as wel...
متن کاملCalbindin-D28k in cortical regions of the lizard Psammodromus algirus.
The morphology, distribution, and ultrastructural features of calbindin-D28k-immunoreactive neurons and fibers in the cortical regions of the lizard Psammodromus algirus, considered homologues to the mammalian hippocampal formation, were analyzed by using the peroxidase anti-peroxidase technique at the light and electron microscopic level. On the basis of staining properties and localization, t...
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ژورنال
عنوان ژورنال: Protein Science
سال: 2000
ISSN: 0961-8368,1469-896X
DOI: 10.1110/ps.9.11.2094